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. They evaluated a lot of than 3,3 hundred men and girls (average age 51) have been offspring with the original subjects who took part in the Framingham Heart Study, a decades long project from the National Heart, Lung and Blood Institute and Boston University
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. They studied 23,000 people and found those with one copy of the allele had a moderately increased risk of heart problems, whilst those with two copies, which accounts for about 20-25 % of white people, have a 30 to 40% higher risk of heart disease than people who carry no copies
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